The ever-increasing pace of technological advancements, rising costs, and new entrants into the health care marketplace are part of the challenge health care incumbents face today. With no alternative but to adapt, health care organizations must find effective methods to embrace innovation, which we define as the delivery of new patient and clinician value. Embedding and accelerating innovation in health care, however, has proven to be difficult. In health care, most current processes of governance, business planning, and information technology implementation are designed to minimize risk to organizations and are often inflexible to adapt quickly to new technological changes, netting incremental changes that fail to deliver much needed transformation.